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1 week ago WEB Jun 1, 2005 · MHC class Ia molecules engage both of the charged termini of typical peptides. H2–M3 mostly ignores the carboxyl (C) terminus, occludes the binding site for the amino (N) terminus and binds N ...
› Author: John R. Rodgers, Richard G. Cook
› Publish Year: 2005
1 week ago WEB Jun 1, 2005 · This work discusses how the subset of MHC class Ib molecules that presents peptides to T cells bridges innate and acquired immunity, and this provides …
1 week ago WEB In addition to the role of HLA-E and Qa-1 during innate immunity, these MHC class Ib molecules can also present microbial antigens to CD8 + T cells. HLA-E and Qa-1 bind …
› Author: Courtney K. Anderson, Laurent Brossay
› DOI: 10.1007/s00251-016-0932-z
› Publish Year: 2016
› Published: 2016/08
1 week ago WEB Jun 1, 2005 · Abstract. Our understanding of the classical MHC class I molecules (MHC class Ia molecules) has long focused on their extreme polymorphism. These …
1 day ago WEB Aug 9, 2011 · MHC class Ib genes, comprising the majority of the class I family, encode molecules that are expressed at lower levels than class Ia and have limited …
4 days ago WEB MHC Class Ib as Innate Pathogen Recognition Molecules. Specific MHC class Ib molecules serve as ligands for T cells expressing “semi-invariant” T cell receptors …
4 days ago WEB The highly polymorphic MHC class Ia molecules have a central role in adaptive immunity. By contrast, the closely related MHC class Ib molecules, which show limited …
3 days ago WEB Sep 1, 2006 · Introduction. The MHC class I molecules are integral to the function of both innate and adaptive immune systems. MHC class Ia (classical) molecules, termed …
3 days ago WEB Feb 12, 2006 · Major histocompatibility complex (MHC) class Ia molecules (HLA-A, HLA-B and HLA-C) have a critical function in the adaptive immune response to viral infections, …
1 day ago WEB MHC class Ib molecules bridge innate and acquired immunity. Nat Rev Immunol 2005; 5:459–71. ... McCluskcy J et al. A structural perspective on MHC class Ib molecules in …
1 week ago WEB Jun 5, 2015 · MHC class Ib molecules bridge innate and acquired immunity. Nat Rev Immunol (2005) 5:459–71. 10.1038/nri1635 [Google Scholar] 35. van Hall T, Laban S, …
1 week ago WEB Aug 20, 2013 · Recent studies have shown that MHC class I molecules play an important role in the protective immune response to M. tuberculosis infection. Both MHC Ia …
1 day ago WEB Feb 1, 2011 · MHC class Ib as innate pathogen recognition molecules. Specific MHC class Ib molecules serve as ligands for T cells expressing ‘semi-invariant’ T cell …
6 days ago WEB The highly polymorphic MHC class Ia molecules have a central role in adaptive immunity. By contrast, the closely related MHC class Ib molecules, which show limited …
2 days ago WEB The mentioned T cell subsets targeting other MHC class Ib molecules, like CD1d, MR1, ... a nonclassical class I histocompatibility molecule with roles in innate and adaptive …
4 days ago WEB Abstract. The highly polymorphic MHC class Ia molecules have a central role in adaptive immunity. By contrast, the closely related MHC class Ib molecules, which show limited …
1 week ago WEB Aug 20, 2013 · 9. Role of human MHC class Ib molecule, HLA-E in tuberculosis. The human HLA class I family comprises both classical (class Ia) and non-classical (class …
1 week ago WEB DOI: 10.1016/J.IT.2006.07.006 Corpus ID: 9606656; A structural perspective on MHC class Ib molecules in adaptive immunity. @article{Sullivan2006ASP, title={A structural …
5 days ago WEB Sep 1, 2006 · The highly polymorphic MHC class Ia molecules have a central role in adaptive immunity.By contrast, the closely related MHC class Ib molecules, which …