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1 week ago WEB The cost of this scrutiny in further testing might be $100,000 - 500,000 (less than if the chemical had been classified as high ). Thus, if the chemical is truly nontoxic, but is misclassified as medium, the cost of the mistake might be a little more than 0.1 unit …
› Published: 1984
1 week ago WEB Sep 7, 2021 · The program starts testing a new group of chemicals each year. The cost of the toxicity testing is fully funded using the budget that is available the year the test is …
› DOI: 10.1111/risa.13810
› Published: 2022/04
› Publication: Risk Anal. 2022 Apr; 42(4)
1 day ago WEB Each example CEA evaluates five hypothetical toxicity-testing methodologies which differ with respect to cost, time, and uncertainty. The results of the examples indicate that …
› Author: Paul S Price, Bryan J Hubbell, Shintaro Hagiwara, Greg M Paoli, Daniel Krewski, Annette Guiseppi-Eli...
› Publish Year: 2021
1 week ago WEB FIGURE 3. The committee’s vision for toxicity testing is a process that includes chemical characterization, toxicity testing, and dose-response and extrapolation modeling. At …
› Author: Daniel Krewski, Daniel Acosta, Melvin Andersen, Henry Anderson, John C. Bailar, Kim Boekelheide, Rob...
› DOI: 10.1080/10937404.2010.483176
› Publish Year: 2010
› Published: 2010/02
1 week ago WEB The framework is specifically designed to explore the trade-offs between cost, timeliness, and uncertainty reduction associated with different toxicity-testing methodologies. The …
3 days ago WEB a toxicity-testing methodology is more cost effective when it enables a correct risk-based decision at a lower cost and/or in less time. The framework also allows for the …
1 week ago WEB Quantitative analyses of misclassification rates in the hazard classification of environmental chemicals: Evaluation of procedures for deriving predicted no-effect …
1 day ago WEB Bookshelf ID: NBK216563 PMID: 25032410 DOI: 10.17226/317. < Prev Next >. Prepared at the request of the National Toxicology Program, this landmark report reveals that many …
1 week ago WEB Mar 1, 2022 · Cognitive diagnosis computerized adaptive testing (CD-CAT) aims to identify each examinee’s strengths and weaknesses on latent attributes for appropriate …
3 days ago WEB Apr 24, 2020 · The ultimate goal of toxicity testing for novel human medicines or any chemical is the identification of any hazardous properties the substance may possess. …
5 days ago WEB Toxicity Testing - NCBI Bookshelf. 1 day ago Web Prepared at the request of the National Toxicology Program, this landmark report reveals that many chemicals used in …
1 week ago WEB Mar 1, 2012 · Second, it will describe the likelihood of misclassification in a situation not addressed in our prior work in which physicians are categorized using statistical testing. …
2 days ago WEB Mar 1, 2022 · Cognitive diagnosis computerized adaptive testing (CD-CAT) aims to identify each examinee's strengths and weaknesses on latent attributes for appropriate …
4 days ago WEB As an example of using R bias to study the bias attributable to misclassification, we investigated whether young drivers are more likely to be involved in drug-influenced fatal …
6 days ago WEB 2 hours ago · Specifically, out of the total estimated discounted costs to industry of $1.17 billion, the average estimated costs of compliance with stages 1 and 2 of the phaseout …
1 week ago WEB Mar 1, 2012 · This content accompanies the article “Physician Cost Profiling—Reliability and Risk of Misclassification,” published in the New England Journal of Medicine ( …
6 days ago WEB Mar 18, 2010 · Results: Median reliabilities ranged from 0.05 for vascular surgery to 0.79 for gastroenterology and otolaryngology. Overall, 59% of physicians had cost-profile scores …
1 week ago WEB Mar 3, 2010 · When percentages were calculated across 26 of the 28 specialties included in the study, 43% of physicians were misclassified as lower cost, and 17% were …
5 days ago WEB Prediction of human toxicity early in the drug development process remains a major challenge. For this, human in vitro models are becoming increasingly important, …
4 days ago WEB These might include differences in health seeking behaviors (screening or diagnostic workups for suspected health problems) , more frequent lab testing for potential liver or …
4 days ago WEB May 29, 2014 · Background: Chemotherapy is expected to reduce cancer deaths (CD), while possibly being harmful in terms of non-cancer deaths (NCD) because of toxicity. …
3 days ago WEB Computerized adaptive testing (CAT) administers items tailored to individual examinees’ ability levels—neither too difficult nor too easy—thereby using fewer items than linear …