2019 Novel Coronavirus 2019 Ncov Covid 19 Disease

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Learn about the CRISPR-Cas based diagnostic tests & Antibody Therapies for COVID19 | Biotechnology | Genetics | Biology

Last updated 2022-01-10 | 4.6

- What is the CRISPR-Cas system?
- Cas12 and Cas13 enzymes for diagnosing infectious diseases
- SHERLOCK CRISPR-Cas13-based diagnostic test kit

What you'll learn

What is the CRISPR-Cas system?
Cas12 and Cas13 enzymes for diagnosing infectious diseases
SHERLOCK CRISPR-Cas13-based diagnostic test kit
Recombinase Polymerase Amplification (RPA)
Detecting test results on paper strip (Lateral Flow Assay)
DETECTOR: CRISPR-Cas12-based COVID-19 Test kit
Loop Mediated Isothermal Amplification (LAMP)
FELUDA: CRISPR-Cas9-based diagnostic test
What is Convalescent Plasma therapy?
How is plasma therapy done?
Advantages and Limitations of Plasma Therapy
Monoclonal antibodies & COVID-19
Types of monoclonal antibodies to be obtained from recovered patients
How monoclonal antibodies can be isolated from COVID-19 recovered patients?
Generation of Human monoclonal antibodies against SARS-CoV-2
How are antibody therapies different from vaccination?

* Requirements

* Knowledge of basic biology
* Motivation to learn

Description

  • What is the CRISPR-Cas system?
  • Cas12 and Cas13 enzymes for diagnosing infectious diseases
  • SHERLOCK CRISPR-Cas13-based diagnostic test kit
  • Recombinase Polymerase Amplification (RPA)
  • Detecting test results on paper strip (Lateral Flow Assay)
  • DETECTOR: CRISPR-Cas12-based COVID-19 Test kit
  • Loop Mediated Isothermal Amplification (LAMP)
  • FELUDA: CRISPR-Cas9-based diagnostic test
  • What is Convalescent Plasma therapy?
  • How is plasma therapy done?
  • Advantages and Limitations of Plasma Therapy
  • Monoclonal antibodies & COVID-19
  • Types of monoclonal antibodies to be obtained from recovered patients
  • How monoclonal antibodies can be isolated from COVID-19 recovered patients?
  • Generation of Human monoclonal antibodies against SARS-CoV-2
  • How are antibody therapies different from vaccination?

Course content

7 sections • 33 lectures

Introduction to coronaviruses 8 lectures

Welcome Lecture Preview 02:22

What are coronaviruses? Preview 08:02

Common cold coronaviruses Preview 03:56

SARS Coronavirus and MERS Coronavirus Preview 05:36

2019 - Novel Coronavirus Preview 01:16

Official name: SARS-CoV-2 and COVID-19 Preview 03:56

Structural proteins of SARS-CoV-2 Preview 01:57

Quiz on coronaviruses

CRISPR-Cas13 based diagnostic test (SHERLOCK) for COVID-19 6 lectures

What is CRISPR-Cas system? Preview 10:45

Cas enzymes for diagnosing infectious diseases Preview 01:52

CRISPR Basics Quiz

Sherlock- CRISPR-Cas based diagnostic kit Preview 07:53

Detecting test results on paper strip (Lateral Flow Assay) Preview 05:30

Quiz on SHERLOCK- CRISPR based diagnostic test

CRISPR-Cas12 based diagnostic test (DETECTR) for COVID-19 4 lectures

Loop Mediated Isothermal Amplification Process (LAMP) Preview 09:31

Cas12 activity Preview 01:33

Detecting test results by Lateral Flow Strip Preview 05:16

Quiz on DETECTR- CRISPR based diagnostic test

CRISPR-Cas12 based diagnostic test (FELUDA) for COVID-19 3 lectures

FELUDA- CRISPR based diagnostic kit Preview 03:24

Detecting test results by Lateral Flow Strip Preview 06:28

Quiz on FELUDA- CRISPR based diagnostic test

Plasma Therapy for the treatment of COVID-19 disease 5 lectures

Convalescent Plasma therapy / Plasma Therapy Preview 06:41

How is plasma therapy done? Preview 03:15

Polyclonal Antibodies & Plasma Therapy Preview 05:29

Limitations of Plasma Therapy Preview 02:43

Quiz on Plasma Therapy

Monoclonal antibody Therapy for the treatment of COVID-19 disease 6 lectures

Monoclonal antibodies & COVID-19 Preview 05:05

Types of monoclonal antibodies to be isolated from COVID-19 recovered patients Preview 01:25

How monoclonal antibodies can be isolated from COVID-19 recovered patients? Preview 05:25

Generation of Human monoclonal antibodies against SARS-CoV-2 Preview 03:55

How are antibody therapies different from vaccination? Preview 03:28

Quiz on Monoclonal Antibody Therapy

Bonus Lecture 1 lectures

***YOUR SPECIAL BONUS*** Preview 00:06